FEP+ calculations predict a stereochemical SAR switch for first-in-class indoline NIK inhibitors for multiple myeloma | Future Drug Discovery
A Kinase Assay for Measuring the Activity of the NIK-IKK1 Complex Induced via the Noncanonical NF-κB Pathway | SpringerLink
A TNF‐p100 pathway subverts noncanonical NF‐κB signaling in inflamed secondary lymphoid organs | The EMBO Journal
p53 suppresses protein levels of NIK and non-canonical NF-κB activity.... | Download Scientific Diagram
p53 suppresses protein levels of NIK and non-canonical NF-κB activity.... | Download Scientific Diagram
NF-κB Inducing Kinase, NIK Mediates Cigarette Smoke/TNFα-Induced Histone Acetylation and Inflammation through Differential Activation of IKKs
NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis | Cell Death & Differentiation
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML
Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice
6MYN: Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to inhibitor R7
The NF-KB pathway and endocrine therapy resistance in breast cancer in: Endocrine-Related Cancer Volume 26 Issue 6 (2019)
Inhibition of nuclear factor kappa B inducing kinase suppresses inflammatory responses and the symptoms of chronic periodontitis in a mouse model - ScienceDirect
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML
Inhibition of nuclear factor kappa B inducing kinase suppresses inflammatory responses and the symptoms of chronic periodontitis in a mouse model - ScienceDirect
A NIK–SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB | Nature
A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. - Abstract - Europe PMC
Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation - Journal of Biological Chemistry
XT2 | NIK inhibitor | Glixxlabs.com High Quality Supplier
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry
Aberrant accumulation of NIK promotes tumorigenicity by dysregulating post-translational modifications in breast cancer | bioRxiv
A TNF‐p100 pathway subverts noncanonical NF‐κB signaling in inflamed secondary lymphoid organs | The EMBO Journal
Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde? | Arthritis Research & Therapy | Full Text
PI3K inhibitors are finally coming of age | Nature Reviews Drug Discovery
Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets | HTML
